The UBE2E3 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to UBE2E3. This antibody recognizes Human, and Mouse antigen. The UBE2E3 Antibody has been validated for the following applications: ELISA, Immunohistochemistry, and Western Blot.
Description
Function: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-and 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. Participates in the regulation of transepithelial sodium transport in renal cells. May be involved in cell growth arrest.
Subunit Structure: The ubiquitin-loaded form interacts specifically with importin-11 (IPO11), leading to its import into the nucleus. Interacts with NEDD4L.
Similarity: Belongs to the ubiquitin-conjugating enzyme family